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Kurzgesagt 19 May 2026 60 here now

The Uncomfortable Truth About Ozempic (Updated Version)

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My mom is on this. She tried for years to lose weight, doing everything she could. However she just couldn’t get food out of her head, and after reaching menopause it got even worse due to the hormone issues leading to even more weight gain. She started taking it and it turned that problem off for her. Because of that, she’s lost over 60 pounds and reduced the inflammation and knees problems. She can now walk farther and enjoy life again. I’m thankful for it, because I get more time with my mom.
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Great video! I was on Zepbound for 6 months. I lost 70 pounds, no longer have hypertension, am no longer pre-diabetic, and have cut my risk of heart disease in half. Once the weight was off, exercising became much easier, so I started running and lifting weights. I have now been off the meds for 4 months and haven't gained back a single pound. Actually lost a bit more. These meds are life-changing for the right person. Just be sure you do what he said, and use the help they give you to build a healthier lifestyle!
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As someone who has raised possums before I love your portrayal of hunger as a little spectral possum familiar of varying influence that everyone carries about with them.
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@bozoli26 From YouTube ↗ 21 Jun 2026 1100
As a scientist formerly in the field of obesity, I find this video remarkably accurate for such simplified explanations. Also, the authors seem to know how extremely important it is to not vilify fat and tackle the issue of overweight, obesity, and satiation from several points, psychological and physiological. Wonderful to see such an instructive video!

The issue the scientific and medical community sees right now isn't the wide-spread use of the drug as much as the lack of titration of the drug per each patient. You want to take only as much of the drug to suppress the hunger to a certain point (not all the way). At the same time, taking too much of the drug may make you more resistant to satiation signals in the future. This would mean that, if in the future you were to stop using the drug, you unfortunately might experience even more hunger. The real long-term effects are yet to be seen. The reason for one-dose-fits-all principle (vs titration) is likely to get the drug faster on the market and into the clinics. The hope is that next generation of drugs would be applied more smartly.
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I'm on week 4 using GLP-1 meds and have lost 3.3kg so far (86.6kg to 83.3kg) without really trying. The biggest change is that I don't think about food all the time anymore. I don't crave snacks, and I can stop eating when I'm full instead of feeling like I have to finish everything on my plate. The most unexpected benefit has been how much quieter my brain feels. I have ADHD, and without the unending food noise, everything feels less urgent. The weight loss is great, but the mental calmness has been the best unexpected effect.

Thank you for the informative video!
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@Stammer6 From YouTube ↗ 21 May 2026 672
I can't imagine how much extra work it was to remake this video, but I sincerely appreciate the effort you guys put into communicating things as clearly as possible.
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@TheDeathstill From YouTube ↗ 21 May 2026 1100
One of the better videos on GLP-1 so far.

I've been on Zepbound since October. Went from 350 to 284. Still got a ways to go.
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as a person using ozempic, its not only the usage, you need to form a habit to eat less, start to train physical strengh, because you will start to feel weak, your water intake will need to go up (at least i always feel dehidrated) and make sure to not eat foods that might feel heavy normally, because you will end up barfing (own experience)
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@hugoware9939 From YouTube ↗ 21 May 2026 1900
As a Pharmacologist I didn’t see the issue with the first video but i’m always happy for another Kurzgesagt video
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Thanks for updating the video, this version is a lot better than the old one. Great work again Kurzgesagt team!
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@Frenotx From YouTube ↗ 21 May 2026 136
Me: "I've probably had enough to eat today"
The possum of infinite hunger: HISSSSS
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@Foxtrot6624 From YouTube ↗ 21 May 2026 1400
If there is one thing Ozempic has done for me is make me incredibly grateful for how apparently low my natural food noise always has been. This was not a phenomenon I’ve ever even thought about before, I often have to remind myself to eat. The idea of eating when im not hungry just doesn’t make sense to me. But when im really hungry, im really really hungry. It’s all I can think about until I get what i need. The idea of living with that in perpetuity sounds completely impossible and I’m very glad people who do experience this now have a safe treatment for it
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Love it when people especially scientists are allowed and even encouraged to update their perspectives based on new data.
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@roflret From YouTube ↗ 21 May 2026 4200
Canada has forced food companies to have giant black warnings on many things. Really has helped me avoid overly fatty/salty things
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@OceanBagel From YouTube ↗ 21 May 2026 5600
This is a lot better than the last one and is exactly what I'd expect from an educational channel. Thanks for revising it!
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@Catspurrly From YouTube ↗ 21 May 2026 4700
I wish we could regulate businesses from creating addictive food instead of putting everyone on a non-obesity subscription.
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@FellowRoach From YouTube ↗ 21 May 2026 8800
HUGE respect to Kurzgesagt for the extra work after hearing the public. That private equity never touch such good channel for humanity.
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@_elsen_ From YouTube ↗ 21 May 2026 13000
I am such a fan of hunger being represented by a hangry opossum
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@Kulkogo From YouTube ↗ 21 May 2026 22000
Thank you for updating this video. Not many people would go out of their way to address criticism of their videos, let alone remake the whole thing in response. It’s stuff like this that really makes you guys stand out from the hundreds of other science channels on this silly platform
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@kurzgesagt From YouTube ↗ 21 May 2026 2500
Do you have a balanced news diet? Go to ground.news/nutshell to see reporting from a variety of sources and perspectives around the world. Subscribe for 40% off their unlimited access Vantage plan through our link.

IMPORTANT:
This is an updated version from the original video we released over a month ago.
The first version did not contain wrong information but our framing was not good enough – after hearing your feedback it was clear that we didn’t communicate the topic well – so we revised the script, made the video longer and added more information and clarifications at key points.

All changes and the link to the original video (now unlisted) can be found here:
Old Version of the Video: https://youtu.be/9t5m33ccUYA
Sources & further reading: sites.google.com/view/sources-ozempic/

This whole experience was annoying because we didn’t plan to make a controversial video – this caused us a lot of extra work but was obviously necessary.
Thanks again for your honest feedback and for helping us get better. We truly appreciate it.